Research Team


Caren Norden

Caren Norden

Principal Investigator

Gulbenkian Institute for Molecular Medicine (GIMM), Oeiras, Portugal

Caren Norden is a German cell and developmental biologist and Principal Investigator at the Gulbenkian Institute for Molecular Medicine (GIMM) in Portugal. Her research focuses on uncovering the mechanisms underlying organ formation using the retina as the main model system. The lab investigates the fundamental principles of retinal morphogenesis, using state-of-the-art imaging and image analysis to generate a quantitative appreciation of the cellular and tissue rearrangements that form the vertebrate eye. They use the developing zebrafish eye and, more recently, also human retinal organoids as model systems.

Dr. Norden has been appointed Darwin Professor of Animal Embryology at the University of Cambridge, joining the Department of Physiology, Development and Neuroscience from April 2026. Her lab will be based at the Gurdon Institute. She is supported by prestigious funding including EMBO membership since 2020 and grants from the European Research Council. Dr. Norden has led internationally recognized labs at the Max Planck Institute of Molecular Cell Biology and Genetics in Dresden and at the Gulbenkian Institute for Molecular Medicine in Lisbon.


Team members collaborating with Caren Norden:


Mario Del Rosario

Mario Del Rosario

Postdoc
ERC Grant

Siân Culley

Siân Culley

Postdoc (now PI)
Wellcome Trust Grant


Publications with our group:


Spatiotemporal Coordination of Guidance Cues Directs Multipolar Migration During Retinal Lamination
Jaakko I Lehtimäki, Jingtao Lilue, Mario Del Rosario, Elisa Nerli, Ricardo Henriques, Caren Norden
Preprint published in bioRxiv, July 2025
Technologies: BioImage Model Zoo (), CARE (), DL4MicEverywhere (), Rescale4DL () and ZeroCostDL4Mic ()
Funded by: CZI, ERC, H2021 and H2022
DOI: 10.1101/2025.07.23.666134
Content-aware image restoration - pushing the limits of fluorescence microscopy
Martin Weigert, Uwe Schmidt, Tobias Boothe, Andreas Müller, Alexandr Dibrov, Akanksha Jain, Benjamin Wilhelm, Deborah Schmidt, Coleman Broaddus, Siân Culley, Mauricio Rocha-Martins, Fabián Segovia-Miranda, Caren Norden, Ricardo Henriques, Marino Zerial, Michele Solimena, Jochen Rink, Pavel Tomancak, Loic Royer, Florian Jug, Eugene W. Myers
Paper published in Nature Methods, November 2018
Technologies: CARE (), NanoJ-SQUIRREL () and NanoJ-SRRF ()
Funded by: BBSRC and Wellcome Trust
News: Technology Networks, VBIO, Innovations Report and Informationsdienst Wissenschaft
DOI: 10.1038/s41592-018-0216-7