Research Team

Romain was a 3-year Postdoc in our research group. Worked on 14 publications. Contributed to 8 technologies. Raised 3 grants. Collaborated with 15 labs. Mentored 1 Masters Student, 1 Internship Student, 2 PhD Students.
Latest news
- 2024-05-13: News outlet Azooptics.com highlights Chamier et al. Biochemical Society Transactions 2019 [external link]
- 2023-11-27: News outlet Photonics.com highlights Laine et al. Nature Methods 2023 [external link]
- 2023-11-20: News outlet The Science Times highlights Laine et al. Nature Methods 2023 [external link]
- 2023-11-16: News outlet Optics.org highlights Laine et al. Nature Methods 2023 [external link]
- 2023-11-14: Blog Springer Nature Protocols and Methods Community highlights Laine et al. Nature Methods 2023 [external link]
Show more news (11 additional items)
- 2023-11-14: News outlet Phys.org highlights Laine et al. Nature Methods 2023 [external link]
- 2022-11-15: News outlet Technology Times highlights Almada et al. Nature Communications 2019 [external link]
- 2022-06-18: News outlet MSN highlights Almada et al. Nature Communications 2019 [external link]
- 2021-11-03: Editorial in Nature Methods highlights Chamier et al. Nature Communications 2021 [external link]
- 2021-05-07: News outlet Expresso highlights Chamier et al. Nature Communications 2021 [external link]
- 2021-04-26: News outlet AZO Life Sciences highlights Chamier et al. Nature Communications 2021 [external link]
- 2021-04-26: News outlet Drug Target Review highlights Chamier et al. Nature Communications 2021 [external link]
- 2021-04-24: News outlet Nanotechnology Now highlights Chamier et al. Nature Communications 2021 [external link]
- 2021-04-24: News outlet The Medical News highlights Chamier et al. Nature Communications 2021 [external link]
- 2021-04-16: Blog Microbiome Digest - Bik's Picks highlights Chamier et al. Nature Communications 2021 [external link]
- 2020-04-21: Editorial in Nature highlights Chamier et al. Nature Communications 2021 [external link]
Supervisees
Collaborations

Christophe Leterrier
Aix Marseille Université, CNRS, INP
Marseille, France
Joint:
11

Loïc Royer
Chan Zuckerberg Biohub
San Francisco, USA
Joint:
2

Séamus Holden
Warwick University
Warwick, UK
Joint:
6

Yoav Shechtman
Technion - Israel Institute of Technology
Haifa, Israel
Joint:
5
Technologies
Latest publications with our group (see more on Google Scholar)
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CLEM-Reg - an automated point cloud-based registration algorithm for volume correlative light and electron microscopy Daniel Krentzel, Matouš Elphick, Marie-Charlotte Domart, Christopher J Peddie, Romain F Laine, Cameron Shand, Ricardo Henriques, Lucy M Collinson, Martin L Jones Paper published in Nature Methods, Setembro 2025 DOI: 10.1038/s41592-025-02794-0 |
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High-fidelity 3D live-cell nanoscopy through data-driven enhanced super-resolution radial fluctuation Romain F. Laine, Hannah S. Heil, Simao Coelho, Jonathon Nixon-Abell, Angélique Jimenez, Theresa Wiesner, Damián Martínez, Tommaso Galgani, Louise Régnier, Aki Stubb, Gautier Follain, Samantha Webster, Jesse Goyette, Aurelien Dauphin, Audrey Salles, Siân Culley, Guillaume Jacquemet, Bassam Hajj, Christophe Leterrier, Ricardo Henriques Paper published in Nature Methods, Novembro 2023 Technologies: CARE (), NanoJ (), NanoJ-eSRRF (), NanoJ-SQUIRREL (), NanoJ-SRRF () and Nuclear-Pores as references Funded by: CZI, EMBO, FCT, H2021, H2022, InnOValley and Wellcome Trust News: Photonics.com, The Science Times, Optics.org and Phys.org Blogs: Springer Nature Protocols and Methods Community DOI: 10.1038/s41592-023-02057-w |
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CLEM-Reg - An automated point cloud based registration algorithm for correlative light and volume electron microscopy Daniel Krentzel, Matouš Elphick, Marie-Charlotte Domart, Christopher J. Peddie, Romain F. Laine, Ricardo Henriques, Lucy M. Collinson, Martin L. Jones Preprint published in bioRxiv, Maio 2023 Technologies: BioImage Model Zoo (), CARE (), CLEM-Reg () and ZeroCostDL4Mic () Funded by: CZI DOI: 10.1101/2023.05.11.540445 |
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Fast4DReg–fast registration of 4D microscopy datasets Joanna W Pylvänäinen, Romain F Laine, Bruno MS Saraiva, Sujan Ghimire, Gautier Follain, Ricardo Henriques, Guillaume Jacquemet Paper published in Journal of Cell Science, Janeiro 2023 Technologies: CARE (), Fast4DReg (), NanoJ () and ZeroCostDL4Mic () Funded by: CZI DOI: 10.1242/jcs.260728 |
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DeepBacs for multi-task bacterial image analysis using open-source deep learning approaches Christoph Spahn, Estibaliz Gómez-de-Mariscal, Romain F. Laine, Pedro M. Pereira, Lucas von Chamier, Mia Conduit, Mariana G. Pinho, Guillaume Jacquemet, Séamus Holden, Mike Heilemann, Ricardo Henriques Paper published in Communications Biology, Julho 2022 Technologies: BioImage Model Zoo (), CARE (), DeepBacs (), NanoJ (), NanoJ-SQUIRREL () and ZeroCostDL4Mic () Funded by: CZI, FCT and Wellcome Trust DOI: 10.1038/s42003-022-03634-z |
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Show more publications (9 additional items)
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Democratising deep learning for microscopy with ZeroCostDL4Mic Lucas von Chamier, Romain F. Laine, Johanna Jukkala, Christoph Spahn, Daniel Krentzel, Elias Nehme, Martina Lerche, Sara Hernández-Pérez, Pieta K. Mattila, Eleni Karinou, Séamus Holden, Ahmet Can Solak, Alexander Krull, Tim-Oliver Buchholz, Martin L. Jones, Loïc A. Royer, Christophe Leterrier, Yoav Shechtman, Florian Jug, Mike Heilemann, Guillaume Jacquemet, Ricardo Henriques Paper published in Nature Communications, Abril 2021 Technologies: CARE (), NanoJ (), NanoJ-SQUIRREL (), NanoJ-SRRF () and ZeroCostDL4Mic () Funded by: EMBO and Wellcome Trust News: AZO Life Sciences, Drug Target Review, Nanotechnology Now and The Medical News Blogs: Microbiome Digest - Bik's Picks DOI: 10.1038/s41467-021-22518-0 |
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Application of Super-Resolution and Advanced Quantitative Microscopy to the Spatio-Temporal Analysis of Influenza Virus Replication Emma Touizer, Christian Sieben, Ricardo Henriques, Mark Marsh, Romain F. Laine Review published in Viruses, Fevereiro 2021 Technologies: NanoJ-VirusMapper, Super-Beacons and ZeroCostDL4Mic () Funded by: Wellcome Trust DOI: 10.3390/v13020233 |
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Single-Molecule Super-Resolution Imaging of T-Cell Plasma Membrane CD4 Redistribution upon HIV-1 Binding Yue Yuan, Caron A. Jacobs, Isabel Llorente Garcia, Pedro M. Pereira, Scott P. Lawrence, Romain F. Laine, Mark Marsh, Ricardo Henriques Paper published in Viruses, Janeiro 2021 Funded by: DOI: 10.3390/v13010142 |
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Avoiding a replication crisis in deep-learning-based bioimage analysis Romain F Laine, Ignacio Arganda-Carreras, Ricardo Henriques, Guillaume Jacquemet Perspective published in Nature methods, Janeiro 2021 Technologies: CARE () and ZeroCostDL4Mic () Funded by: EMBO and Wellcome Trust DOI: 10.1038/s41592-021-01284-3 |
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An Introduction to Live-Cell Super-Resolution Imaging Siân Culley, Pedro Matos Pereira, Romain F Laine, Ricardo Henriques Book chapter published in Imaging from Cells to Animals In Vivo, Janeiro 2020 Technologies: CARE (), NanoJ (), NanoJ-Fluidics (), NanoJ-SQUIRREL () and QuickPALM DOI: 10.1201/9781315174662-4 |
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Fluctuation-based super-resolution traction force microscopy Aki Stubb, Romain F Laine, Mitro Miihkinen, Hellyeh Hamidi, Camilo Guzmán, Ricardo Henriques, Guillaume Jacquemet, Johanna Ivaska Paper published in Nano letters, Janeiro 2020 Technologies: FBSR-TFM, NanoJ (), NanoJ-SQUIRREL () and NanoJ-SRRF () Funded by: BBSRC DOI: 10.1021/acs.nanolett.9b04083 |
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Artificial intelligence for microscopy - what you should know Lucas von Chamier, Romain F. Laine, Ricardo Henriques Review published in Biochemical Society Transactions, Julho 2019 Technologies: CARE (), NanoJ (), NanoJ-Fluidics (), NanoJ-SQUIRREL () and NanoJ-SRRF () Funded by: BBSRC and Wellcome Trust News: Azooptics.com DOI: 10.1042/bst20180391 |
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Automating multimodal microscopy with NanoJ-Fluidics Pedro Almada, Pedro M. Pereira, Siân Culley, Ghislaine Caillol, Fanny Boroni-Rueda, Christina L. Dix, Guillaume Charras, Buzz Baum, Romain F. Laine, Christophe Leterrier, Ricardo Henriques Paper published in Nature Communications, Março 2019 Technologies: NanoJ (), NanoJ-Fluidics (), NanoJ-SQUIRREL (), NanoJ-SRRF () and NanoJ-VirusMapper Funded by: BBSRC and Wellcome Trust News: Technology Times, MSN, DNYUZ and Express Informer DOI: 10.1038/s41467-019-09231-9 |
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NanoJ - a high-performance open-source super-resolution microscopy toolbox Romain F Laine, Kalina L Tosheva, Nils Gustafsson, Robert D M Gray, Pedro Almada, David Albrecht, Gabriel T Risa, Fredrik Hurtig, Ann-Christin Lindås, Buzz Baum, Jason Mercer, Christophe Leterrier, Pedro M Pereira, Siân Culley, Ricardo Henriques Paper published in Journal of Physics D - Applied Physics, Janeiro 2019 Technologies: CARE (), NanoJ (), NanoJ-Fluidics (), NanoJ-SQUIRREL (), NanoJ-SRRF (), NanoJ-VirusMapper and QuickPALM Funded by: BBSRC and Wellcome Trust DOI: 10.1088/1361-6463/ab0261 |
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Latest funding with our group
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Beyond protein localization - monitoring molecular function with nanometer sensitivity Ricardo Henriques, Romain Laine, Takeharu Nagai, Kai Lu Funded by: UCL - Strategic Partner Fund - Establishing collaborative research between UCL and Osaka University Duration: Setembro 2019 - Agosto 2020 |
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Establishing collaborative research between UCL and Institut Curie Ricardo Henriques, Romain Laine, Bassam Hajj Funded by: UCL - Cities Partnership Programme Duration: Junho 2019 - Junho 2019 |