Research Team


Estibaliz Gómez de Mariscal

Estibaliz Gómez de Mariscal

Postdoc


Started in: October 2021

Funding: EMBO Installation Grant; EMBO Fellowship


Estibaliz is a 4th-year Postdoc in our research group. Worked on 11 publications. Contributed to 6 technologies. Raised 2 grants. Collaborates with 10 labs. Mentored 2 Software Engineers.

Overview: I'm interested in understanding cell-level biology using bioimage analysis. My research centers on facing the challenges when applying machine-learning techniques to microscopy images and on contributing to biological discoveries with it. Previously, I developed methods to process TEM images and phase-contrast time-lapse movies to contribute to the characterization of cancer cell motility. I have also conceived new biostatistical approaches to analyse big data. I'm also one of the creators of deepImageJ, an environment to bridge deep-learning to ImageJ. A crucial part of my work and dedication is to make computational tools accessible (open and user-friendly) and reusable, and train non-experts to benefit from them. As a postdoc in Ridardo's lab I'll be learning (a lot) of super-resolution microscopy, and building novel machine-learning methodologies applied to it.


Latest news

  • 2025-04-22: Blog BPoD - Biomedical Picture of the Day highlights Spahn et al. Nature Communications 2025 [external link]
  • 2024-06-02: News outlet Labonline highlights Hidalgo-Cenalmor et al. Nature Methods 2024 [external link]
  • 2024-05-28: News outlet MSN highlights Hidalgo-Cenalmor et al. Nature Methods 2024 [external link]
  • 2024-05-27: News outlet Aamuset Kaupunkimedia highlights Hidalgo-Cenalmor et al. Nature Methods 2024 [external link]
  • 2024-05-17: Blog news-medical.net highlights Hidalgo-Cenalmor et al. Nature Methods 2024 [external link]
Show more news (2 additional items)

Supervisees

Iván Hidalgo-Cenalmor

Iván Hidalgo-Cenalmor

Software Engineer
H2021 AI4Life Grant funded

Mariana Ferreira

Mariana Ferreira

Software Engineer
H2021 AI4Life Grant funded


Collaborations

Anna Kreshuk

Anna Kreshuk

EMBL
Heidelberg, Germany

Joint: 1 2

Arrate Muñoz-Barrutia

Arrate Muñoz-Barrutia

Universidad Carlos III de Madrid
Madrid, Spain

Joint: 2 1

Florian Jug

Florian Jug

Human Technopole
Milan, Italy

Joint: 3 1

Guillaume Jacquemet

Guillaume Jacquemet

Abo Akademi University
Turku, Finland

Joint: 17 1

Mariana Pinho

Mariana Pinho

ITQB NOVA
Oeiras, Portugal

Joint: 5 1 2

Mike Heilemann

Mike Heilemann

Goethe University
Frankfurt, Germany

Joint: 6 1

Pedro Matos Pereira

Pedro Matos Pereira

ITQB NOVA
Oeiras, Portugal

Joint: 9 3

Séamus Holden

Séamus Holden

Warwick University
Warwick, UK

Joint: 5

Wei Ouyang

Wei Ouyang

SciLifeLab
Stockholm, Sweden

Joint: 2 1

Yoav Shechtman

Yoav Shechtman

Technion - Israel Institute of Technology
Haifa, Israel

Joint: 5


Technologies

BioImage Model Zoo BioImage Model Zoo Newest update: 2025-07-04
Rescale4DL Rescale4DL Newest update: 2025-04-24
DL4MicEverywhere DL4MicEverywhere Newest update: 2025-04-20
PhotoFiTT PhotoFiTT Newest update: 2025-03-13
CellTracksColab CellTracksColab Newest update: 2025-03-11
DeepBacs DeepBacs Newest update: 2022-7-9

Latest Outreach

Our Lab's Participation in ITQB NOVA's Open Day ITQB NOVA's Open Day ITQB NOVA, Oeiras - Portugal March 2025
Celebrating Women in Science with ITQB NOVA International Day of Women in Science ITQB NOVA, Oeiras - Portugal February 2025

Latest publications with our group (see more on Google Scholar)

The nucleoid of rapidly growing Escherichia coli localizes close to the inner membrane and is organized by transcription, translation, and cell geometry
Christoph Spahn, Stuart Middlemiss, Estibaliz Gómez-de-Mariscal, Ricardo Henriques, Helge B. Bode, Séamus Holden, Mike Heilemann
Paper published in Nature Communications, April 2025
Technologies: CARE (), DeepBacs () and ZeroCostDL4Mic ()
Funded by: EMBO, ERC, H2021 and H2022
Blogs: BPoD - Biomedical Picture of the Day
DOI: 10.1038/s41467-025-58723-4
ReScale4DL - Balancing Pixel and Contextual Information for Enhanced Bioimage Segmentation
Mariana G. Ferreira, Bruno M. Saraiva, António D. Brito, Mariana G. Pinho, Ricardo Henriques, Estibaliz Gómez-de-Mariscal
Preprint published in bioRxiv, April 2025
Technologies: BioImage Model Zoo (), DeepBacs (), DL4MicEverywhere (), NanoPyx (), Rescale4DL () and ZeroCostDL4Mic ()
Funded by: CZI, EMBO, ERC, H2021 and H2022
DOI: 10.1101/2025.04.09.647871
PhotoFiTT - A Quantitative Framework for Assessing Phototoxicity in Live-Cell Microscopy Experiments
Mario Del Rosario, Estibaliz Gómez-de-Mariscal, Leonor Morgado, Raquel Portela, Guillaume Jacquemet, Pedro M. Pereira, Ricardo Henriques
Preprint published in bioRxiv, July 2024
Technologies: DL4MicEverywhere (), PhotoFiTT () and ZeroCostDL4Mic ()
Funded by: CZI, EMBO, ERC, FCT, H2021 and H2022
DOI: 10.1101/2024.07.16.603046
DL4MicEverywhere - deep learning for microscopy made flexible, shareable and reproducible
Iván Hidalgo-Cenalmor, Joanna W. Pylvänäinen, Mariana G. Ferreira, Craig T. Russell, Alon Saguy, Ignacio Arganda-Carreras, Yoav Shechtman, Guillaume Jacquemet, Ricardo Henriques, Estibaliz Gómez-de-Mariscal
Paper published in Nature Methods, May 2024
Technologies: BioImage Model Zoo (), DL4MicEverywhere () and ZeroCostDL4Mic ()
Funded by: EMBO, ERC, H2021 and H2022
News: Labonline, MSN, AZoRobotics and Aamuset Kaupunkimedia
Blogs: news-medical.net
DOI: 10.1038/s41592-024-02295-6
Harnessing artificial intelligence to reduce phototoxicity in live imaging
Estibaliz Gómez-de-Mariscal, Mario Del Rosario, Joanna W. Pylvänäinen, Guillaume Jacquemet, Ricardo Henriques
Perspective published in Journal of Cell Science, February 2024
Technologies: BioImage Model Zoo (), CARE (), DeepBacs (), NanoJ-eSRRF (), NanoJ-SQUIRREL (), NanoJ-SRRF () and ZeroCostDL4Mic ()
Funded by: CZI, EMBO, ERC, H2021 and H2022
DOI: 10.1242/jcs.261545
Show more publications (6 additional items)
CellTracksColab is a platform that enables compilation, analysis, and exploration of cell tracking data
Estibaliz Gómez-de-Mariscal, Hanna Grobe, Joanna W Pylvänäinen, Laura Xénard, Ricardo Henriques, Jean-Yves Tinevez, Guillaume Jacquemet
Published in PLOS Biology, January 2024
Technologies: CARE (), CellTracksColab () and ZeroCostDL4Mic ()
DOI: 10.1371/journal.pbio.3002740
Transertion and cell geometry organize the Escherichia coli nucleoid during rapid growth
Christoph Spahn, Stuart Middlemiss, Estibaliz Gómez-de-Mariscal, Ricardo Henriques, Helge B. Bode, Séamus Holden, Mike Heilemann
Preprint published in bioRxiv, October 2023
Technologies: CARE (), DeepAutoFocus (), DeepBacs () and ZeroCostDL4Mic ()
Funded by: EMBO, ERC, H2021 and H2022
DOI: 10.1101/2023.10.16.562172
Live-cell imaging in the deep learning era
Joanna W Pylvänäinen, Estibaliz Gómez-de-Mariscal, Ricardo Henriques, Guillaume Jacquemet
Review published in Current Opinion in Cell Biology, January 2023
Technologies: BioImage Model Zoo (), CARE (), DeepBacs (), Fast4DReg (), NanoJ (), NanoJ-Fluidics () and ZeroCostDL4Mic ()
Funded by: CZI, EMBO, ERC and H2021
DOI: 10.1016/j.ceb.2023.102271
Roadmap on deep learning for microscopy
Giovanni Volpe, Carolina Wählby, Lei Tian, Michael Hecht, Artur Yakimovich, Kristina Monakhova, Laura Waller, Ivo F Sbalzarini, Christopher A Metzler, Mingyang Xie, Kevin Zhang, Isaac CD Lenton, Halina Rubinsztein-Dunlop, Daniel Brunner, Bijie Bai, Aydogan Ozcan, Daniel Midtvedt, Hao Wang, Nataša Sladoje, Joakim Lindblad, Jason T Smith, Marien Ochoa, Margarida Barroso, Xavier Intes, Tong Qiu, Li-Yu Yu, Sixian You, Yongtao Liu, Maxim A Ziatdinov, Sergei V Kalinin, Arlo Sheridan, Uri Manor, Elias Nehme, Ofri Goldenberg, Yoav Shechtman, Henrik K Moberg, Christoph Langhammer, Barbora Špačková, Saga Helgadottir, Benjamin Midtvedt, Aykut Argun, Tobias Thalheim, Frank Cichos, Stefano Bo, Lars Hubatsch, Jesus Pineda, Carlo Manzo, Harshith Bachimanchi, Erik Selander, Antoni Homs-Corbera, Martin Fränzl, Kevin de Haan, Yair Rivenson, Zofia Korczak, Caroline Beck Adiels, Mite Mijalkov, Dániel Veréb, Yu-Wei Chang, Joana B Pereira, Damian Matuszewski, Gustaf Kylberg, Ida-Maria Sintorn, Juan C Caicedo, Beth A Cimini, Muyinatu A Lediju Bell, Bruno M Saraiva, Guillaume Jacquemet, Ricardo Henriques, Wei Ouyang, Trang Le, Estibaliz Gómez-de-Mariscal, Daniel Sage, Arrate Muñoz-Barrutia, Ebba Josefson Lindqvist, Johanna Bergman
Preprint published in arXiv, January 2023
Technologies: BioImage Model Zoo (), CARE () and ZeroCostDL4Mic ()
Funded by: CZI, EMBO, ERC and H2021
DOI: 10.48550/arXiv.2303.03793
DeepBacs for multi-task bacterial image analysis using open-source deep learning approaches
Christoph Spahn, Estibaliz Gómez-de-Mariscal, Romain F. Laine, Pedro M. Pereira, Lucas von Chamier, Mia Conduit, Mariana G. Pinho, Guillaume Jacquemet, Séamus Holden, Mike Heilemann, Ricardo Henriques
Paper published in Communications Biology, July 2022
Technologies: BioImage Model Zoo (), CARE (), DeepBacs (), NanoJ (), NanoJ-SQUIRREL () and ZeroCostDL4Mic ()
Funded by: CZI, ERC, FCT and Wellcome Trust
DOI: 10.1038/s42003-022-03634-z
Bioimage model zoo - a community-driven resource for accessible deep learning in bioimage analysis
Wei Ouyang, Fynn Beuttenmueller, Estibaliz Gómez-de-Mariscal, Constantin Pape, Tom Burke, Carlos Garcia-López-de-Haro, Craig Russell, Lucía Moya-Sans, Cristina de-la-Torre-Gutiérrez, Deborah Schmidt, Dominik Kutra, Maksim Novikov, Martin Weigert, Uwe Schmidt, Peter Bankhead, Guillaume Jacquemet, Daniel Sage, Ricardo Henriques, Arrate Muñoz-Barrutia, Emma Lundberg, Florian Jug, Anna Kreshuk
Preprint published in BioRxiv, January 2022
Technologies: BioImage Model Zoo (), CARE () and ZeroCostDL4Mic ()
Funded by: CZI, EMBO, ERC and H2021
DOI: 10.1101/2022.06.07.495102

Latest funding with our group

SMALS - Smart Microscopy for Adaptative Live Super-resolution imaging to elucidate the initial steps of the HIV viral transmission
Estibaliz Gómez-de-Mariscal
Alias: SMALS
Funded by: FCT - CEEC Individual
Duration: April 2024 - March 2027
A transformative data-driven live-cell super-resolution microscopy development to elucidate the initial steps of effective viral transmission
Estibaliz Gómez-de-Mariscal
Funded by: EMBO - Postdoctoral Fellowships
Duration: July 2022 - June 2024
Publications: 9